RO9021 Angled Neck

RO9021 Angled NeckRO9021 potently inhibits SYK kinase activity with an average IC50 of 5. 6 nM and suppresses B cell receptor signaling.

Magnolol is a bioactive lignin found in the bark of the Houpu magnolia (Magnolia officinalis) which shows antifungal properties

25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3

Its half-life is about 34-38 hours

Ceftezole is a semi-synthetic first-generation cephalosporin with antibacterial activity

Picroside II is the main active ingredient in iridoid glycosides

NU2058 is an inhibitor of CDK2 with IC50 value of 17

B stimulation

no activity towards Erk1

an isoflavones found in the root of Radix puerariae

Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV

Diaveridine is coccidiostat with anti-parasitic activity and also a dihydrofolate reductase (DHFR) inhibitor preventing folic acid synthesis in species of Pneumocystis

used as a sedative and muscle relaxant